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It is mediated by specialized sensory cells of the nasal cavity, which can be considered analogous to sensory cells of the antennae of invertebrates.
In humans, olfaction occurs when odorant molecules bind to specific sites in the olfactory receptors inside the nose.
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At the same time, a growing body of research suggests that a person's genetic compatibility, gender, age, and predisposition to illness are reflected in their "smell signature." Even in blinded experiments, subjects' smell preferences align broadly with their sexual desires. Wedekind, Claus, Thomas Seebeck, Florence Bettens, and Alexander J. "MHC-dependent mate preferences in humans." Proceedings of the Royal Society of London B: Biological Sciences 260, no. Project by Tega Brain in collaboration with Sam Lavigne and Useless Press. However when it comes to long-term romantic partnership it may actually be riskier to ignore the powerful signal of scent than to rely on it.