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04-Feb-2017 10:05

However, in the last 2-3 years in Cambodia/Thai border we have identified strains of P.falciparum which appear to be at least partially resistant to the artemisinins: parasite clearance rates are much slower than usual.

If these resistant strains spread, particularly to Africa, then it will lead to a major public health disaster. For a number of reasons, South East Asia is the home to the most resistant malaria parasites in the world.

So after my training in the UK, first at Cambridge and then in Oxford for my postgraduate biomedical training, I was lucky to be where there were already established research groups working in the tropics, and I talked to people who were involved, Professors.

David Warrell and Nick White, and so moved to the major overseas programme based in Vietnam.

There are some drugs in the pipeline but it is unclear whether any of them will be able to take centre stage.

Some of the new drugs have the same mechanism of action as the artemisinins but are synthetic.

So from the age of about 12, I wanted to become a doctor, and to study tropical medicine.

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A great deal of news footage has been written in the last few years about the prospects of not just malaria control, but eradication: artemisinin resistance is a major threat to this.

Nguyen Hoan Phu who had an enormous wealth of clinical experience treating these tropical infections, worked with us and were able to teach me about tropical infections: how to diagnose and treat them.



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